下肢缺血是研究血管再生和缺血性血管新生的通用實驗模型，廣泛應用于外周血管疾病、重度下肢缺血、糖尿病足、截肢水平、血管新生、缺血保護與耐受、缺血再灌注損傷等方面的研究與評價，同時也是下肢缺血動物模型制備中必要的評價手段。

激光多普勒成像可被用于無創評價大小鼠下肢的系統性血流灌注，同時也不需要追蹤染料。這使我們可以將結扎限流的下肢血流與對照下肢進行比較。檢測可在很多天內持續進行，因此可以評價由血管再生而產生的再灌注進程。對于促血管再生性治療，血流將快速恢復到基線（100%），即與對照肢相同的水平。對于抑制血管再生性實驗，血流將更慢地恢復到正常的基線水平。

缺血手術后血流恢復狀況

相關產品

moorLDI2-HIR點掃描激光多普勒成像系統                                                   moorFLPI-2激光散斑血流成像

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